Dietary Supplements As Anti Inflammatory
While inflammation can be a natural response to an injury or infection, chronic low-grade inflammation can contribute to heart disease, cancer and type 2 diabetes. Dietary supplements can help reduce inflammation naturally.
SAM-e (S-adenosylmethionine) is produced naturally in the body and helps regulate genes that control the inflammatory response. It can also relieve pain and lower triglyceride levels.
Omega-3 fatty acids
Omega-3 fatty acids are components of the phospholipids that make up the structures of cell membranes. They are concentrated at high levels in the retina, brain, and sperm . These fats provide energy and help the body form eicosanoids that have many important functions, including controlling inflammation, vasoconstriction, and platelet aggregation.
The omega-3 fatty acids found in foods are ALA (alpha-linolenic acid), EPA, and DHA. ALA is found in plant oils and can be converted to EPA and DHA by the body. However, this process only provides a small amount of these fats. Therefore, consuming foods rich in omega-3 fatty acids is essential.
Studies have linked higher intakes of fish or dietary supplements containing EPA and DHA to reduced risk for heart disease. This is due to their ability to lower blood triglyceride levels. These effects also extend to other metabolic processes, such as glucose regulation. Additionally, these fats are associated with reduced inflammation and improved symptoms in conditions such as rheumatoid arthritis and dry eye.
Coenzyme Q10 is made naturally in the body, where it helps generate energy for cell growth and protects cells from damage. It also acts as an antioxidant to counteract oxidative stress from too much free radicals. It exists in two forms, ubiquinol and ubiquinone; the body is able to convert back and forth between them.
A randomized controlled trial of patients undergoing coronary angioplasty showed that supplemental coenzyme Q10 significantly increased blood flow to the heart during the procedure (44). It was also associated with lower concentrations of C-reactive protein and less inflammation in the blood.
Coenzyme Q10 is likely effective in alternative medicine as a supplement for migraine headaches, reducing the symptoms of mitochondrial disorders such as Huntington’s disease and muscular dystrophy, lowering blood pressure and preventing a second heart attack in people who have already had one, enhancing physical performance in people with congestive heart failure, and slowing the progression of early Parkinson’s disease (45). More research is needed to support these uses.
Green tea extract
Green tea extract and its constituents have a wide range of potential benefits for the body, from aiding weight loss and energy levels to decreasing heart disease risk factors. However, higher doses of the ingredient EGCG may cause liver damage in some people.
This is especially important to keep in mind if you have preexisting liver problems. Green tea has also been linked to skin health and may help reduce acne breakouts and aging symptoms. Its antioxidant properties have been shown to decrease oxidative stress, which can lead to cellular aging and promote diseases like diabetes and high blood pressure.
A small study showed that consuming green tea reduced total and LDL cholesterol levels in people with type II diabetes. This could help prevent heart disease by reducing the buildup of fats in the arteries and lowering blood pressure (6). This benefit was attributed to EGCG, which inhibited fat absorption in cells and increased fat oxidation in the liver (7).
S-adenosylmethionine is a naturally occurring compound in the body that enables a number of essential metabolic reactions. It is available in the United States as a dietary supplement and as a prescription drug in some European countries. It is sometimes used to treat depression, osteoarthritis, and fibromyalgia. It also serves as a primary methyl group donor for phase II hepatic detoxification and for biosynthesis of nucleic acids, proteins, phospholipids, creatine, melatonin and other molecules.
A natural product that is made by the body and found in many foods, SAMe has been shown to have antidepressant, arthritic and liver-protective effects. However, more research is needed to determine whether it has a role in reducing the symptoms of fibromyalgia. When taking SAMe, it is important to follow the instructions on the label and avoid other supplements that may interact with it. It is also best to store the supplements in a cool, dry place. This will help to preserve their potency.Read More
In today’s dynamic world of online gaming and sports betting, the traction towards safe playgrounds, or 안전놀이터, continues to rise. It’s not just about enjoyment anymore; it’s about engaging in a digital space where you can have fun without compromising your safety. Now that raises a critical question – how do we ensure that these virtual playgrounds remain secure for enthusiasts around the globe?
Finding a secure playground for your online activities involves more than just a quick Google search. It’s about delving deeper into the reputation of these sites. Trustworthiness forms the backbone of 안전놀이터, as it assures users that their personal and financial information remains protected against any nefarious elements lurking in the vast expanses of the internet.
Imagine logging onto your favorite gaming site and knowing that every click leads you further into a shielded domain where safety isn’t just promised – it’s a given. That peace of mind is the hallmark of a truly secure online environment. But let’s take this further – what if this assurance also came with top-notch customer service, iron-clad privacy policies, and an array of games that are not only entertaining but also operate under fair play guidelines?
It’s like walking into a playground where the ground is soft enough to cushion your fall, yet solid enough to keep you grounded. You know you won’t get hurt, and if you do, there’s someone to tend to your needs instantly. But why stop at safety? These playgrounds often come with the added benefit of community – a place where you can interact with fellow enthusiasts, share tips, and celebrate victories, all within a safe and monitored environment.
Now, let’s draw toward a conclusion. The internet, vast and wild, holds within it pockets of sanctuary where the digital and the secure intertwine. These safe playgrounds, these 안전놀이터, are not mere outlets for amusement but bastions of security in an online world. Knowing where you stand, your rights, and how these sites ensure your safety is key to fully enjoying the online gaming experience.
1. What exactly is an 안전놀이터?
An 안전놀이터, or safe playground, refers to an online platform where users can play games and engage in betting activities within a secure environment that protects their personal and financial information.
2. How do I know if a site is a secure playground?
Look for reviews, check the site’s licensing and security policies, ensure they have SSL encryption, and observe whether they have a reliable customer support system.
3. Why is choosing a safe playground important?
Choosing a safe playground is crucial to protect yourself from identity theft, fraud, and to ensure fair play in games and betting.
4. Are there specific features that make a gaming site a secure playground?
Yes, features such as SSL encryption, verified payment methods, licenses from recognized authorities, and software audited for fair play contribute to making a gaming site a secure playground.
5. Can international users access 안전놀이터?
Yes, many secure playgrounds are accessible internationally, but ensure they support your language and currency and comply with your country’s gaming regulations.…Read More
Supplements Good For Inflammation
Inflammation is a natural process that heals wounds, boosts blood flow to damaged tissues and alerts us to problems by causing pain. But if the inflammation lasts too long, it can lead to serious conditions such as heart disease and diabetes.
Vitamins and herbs can help reduce inflammation. Supplements good for inflammation include omega-3 fatty acids, curcumin and green tea extract.
Omega-3 fatty acids
Omega-3 fatty acids, also called polyunsaturated fatty acids, are essential to your health. They are found in foods like fish and shellfish, as well as dietary supplements such as fish oil and flaxseed. These fats are known for their ability to reduce inflammation in the body.
The omega-3 fatty acids found in seafood are called eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Your body can’t make these omega-3 fatty acids, so you need to get them from your diet. They’re found in fatty fish, such as salmon, mackerel and trout, and some plant oils, such as flaxseed and canola oil.
Studies show that omega-3 fatty acids can help treat many inflammatory conditions. They may improve the symptoms of rheumatoid arthritis, and they can help lower cholesterol levels, blood pressure and triglycerides. They may even help prevent or delay the onset of heart disease. In one study, omega-3 fatty acids reduced the frequency of paroxysmal atrial fibrillation episodes.
Curcumin is a powerful antioxidant that can suppress many molecules that promote inflammation. It also has antimicrobial properties that may help prevent and treat various diseases. However, more research is needed to determine the best dosage for this supplement.
In a placebo-controlled pilot study, 20 healthy male athletes were given either 1 g of curcumin twice daily or a placebo before and after a downhill running test. The curcumin group experienced significantly less pain in their right and left anterior thigh muscles. They also had lower levels of the inflammatory markers c-reactive protein and myeloperoxidase, but not of plasma glutathione peroxidase or salivary amylase.
Another study found that curcumin can improve the function of endothelial cells, which line blood vessels and play a critical role in regulating blood pressure and other factors. Poor endothelial cell function is a major factor in heart disease. In addition, curcumin can reduce insulin resistance, high triglyceride levels and elevated blood pressure.
Green tea extract
Green tea extract contains powerful antioxidants called catechins, including epigallocatechin gallate (EGCG). It’s been shown to decrease fat accumulation and prevent high blood pressure. In addition, it stimulates metabolism and helps you burn fat. It also improves digestion and boosts energy. Several animal and human studies have linked green tea to decreased risk of cardiovascular disease, diabetes, inflammation, cancer and other health conditions.
It’s important to talk with your doctor before adding a green tea supplement to your diet. In some cases, excessive intake can result in liver damage and a number of other side effects.
A recent study found that EGCG inhibits the formation of neutrophil-endothelial cell adhesion molecules, which can lead to inflammatory responses. It also decreases the production of proinflammatory cytokines and decreases expression of destructive matrix metalloproteinases. This reduces the oxidative stress that causes fat to build up in the arteries, leading to high blood pressure. It also promotes the growth of new, healthy tissue and increases skin elasticity.
S-adenosylmethionine (SAMe) is a naturally occurring compound in the body that enables a number of essential metabolic reactions. It is available as a dietary supplement in the US and as a prescription drug in some European countries. It is used to treat depression, osteoarthritis and liver disease. It is also reported to reduce pain and has some anti-inflammatory properties.
Several studies have found that adjunctive SAMe treatment enhances the antidepressant effects of standard treatments. However, large randomized controlled trials are needed to confirm these findings and establish the optimal dosage of SAMe.
SAMe is well tolerated and has few side effects. Some people may experience mania after taking SAMe, but this is rare. Some medications and dietary supplements can interact with SAMe, so it is important to discuss all of your medications with a healthcare provider before taking this supplement. SAMe is not recommended for pregnant women or breastfeeding mothers. It is also not safe for anyone who has bipolar disorder.Read More
Thorne Supplements and Mitsui Onegevity
The company’s products help people live healthier and longer. They use testing and data to create personalized solutions for consumers, health professionals, and corporations. They also partner with experts, including medical doctors, naturopathic doctors, and trainers.
This communication contains forward-looking statements. All statements other than statements of historical facts are forward-looking and include, but are not limited to, the expected completion of the transaction.
Thorne HealthTech is a leading premium, high-quality nutritional supplement manufacturer and direct-to-consumer e-commerce platform. It owns every step of the manufacturing process at its NSF International, Therapeutics Goods Administration-certified facility in Summerville, South Carolina and sources the highest quality raw materials. The company also offers a wide range of at-home health tests and supplements to support sleep, fertility, stress, and gut health.
L Catterton is a private equity firm with over 250 investments and a broad portfolio of brands across all consumer segments. The firm’s category-first approach is designed to understand consumer preferences and identify consumer categories that are well suited to its investment strategy. Among its many recent successes, the Greenwich, Connecticut-based firm is credited with funding boutique fitness brands such as CorePower Yoga and Pure Barre. It also holds a significant stake in the popular Rihanna Savage x Fenty lingerie line.
Mitsui & Kirin
Mitsui is a Japanese corporate group and keiretsu that traces its roots to the zaibatsu groups that were dissolved after World War II. The company is involved in a wide range of businesses including trading and distribution of food and health products, construction and real estate, and energy. It also has a large stake in Abellio Greater Anglia and IHH Healthcare Berhad.
Kirin and Mitsui’s joint investment will strengthen each company’s initiatives in global preventive health management and wellness, which are becoming important societal issues in the U.S and Japan. In addition, Kirin’s investment will enhance the development of new supplements based on its Lactococcus plasma technology, a spokesperson told NutraIngredients-Asia.
The deal comes at a time when M&A activity in the nutrition industry has hit a wall. According to Nutrition Capital Network, deals through June of this year totaled only 499, a far cry from the 1,500 deals that took place in the same period last year.
Onegevity is a new health intelligence company that has developed a multi-omic artificial intelligence (AI) platform with user-friendly at-home tests, products, and digital health services. Its mission is to use this technology to help people uncover health insights and confidently take action to optimize their wellness.
The company’s products include a variety of nutrition supplements that can be used to improve the health of your gut microbiome and support your body’s natural detoxification processes. They also provide personalized supplement recommendations based on your goals. Their reports include data from your genetic and metabolomic profiles, as well as probabilistic feedback from others who are similar to you.
The company’s management team has extensive experience in the natural and organic food industry. They have a track record of creating profitable companies and delivering growth through acquisitions and strategic investments. The company was recently acquired by L Catterton, a private equity firm that manages more than $30 billion in assets. The transaction is expected to be completed in the fourth quarter of 2023, subject to customary closing conditions and regulatory approvals.
The company is a developer, manufacturer and supplier of high-quality supplements that are backed by extensive scientific evidence. It sells its products through health professionals and direct-to-consumer channels. It also offers at-home gut health tests that are designed to track changes in a person’s microbiome.
This deal comes at a time when M&A activity in the nutrition industry has hit a wall, and some are likening it to the mini-ice age that occurred late 2008 and into 2009. According to Nutrition Capital Network data, there were just 499 transactions in the first six months of 2022, compared to 699 and 641 during the same period in the previous two years.
Thorne’s dedication to clean, potent ingredients and strict manufacturing standards makes its products a top choice for many consumers. Its supplements can be used to fill nutritional gaps or support a healthy lifestyle. In addition, its specialized formulations may help people with specific health needs.Read More
David Sinclair, MD, Takes Supplements to Promote Health and Slow Aging
David Sinclair, a longevity researcher and author of the book Lifespan, takes several supplements to promote health and slow aging. His regimen includes resveratrol, NMN (nicotinamide mononucleotide), spermidine, quercetin, and fisetin.
He also takes metformin, a prescription diabetes medication that has anti-aging properties. He takes it in the morning with a spoonful of yogurt.
A vitamin D supplement can help improve immunity and boost calcium absorption, which helps maintain healthy bones. It is also thought to reduce cancer risk, decrease inflammation and prevent cardiovascular disease.
A low dose of aspirin can help reduce inflammation and the risk of heart attack or stroke. It is important to consult with a physician before taking aspirin, as it may cause stomach damage or bleeding in some people.
David Sinclair also takes Coenzyme Q10, which is an antioxidant that enhances mitochondrial function. He recommends taking it in the morning, which coincides with the natural rise in NAD and Sirt-1 levels in the body.
Vitamin K2 is a fat-soluble vitamin important for blood clotting. It is also involved in bone formation and osteoporosis prevention. It also activates sirtuins and inhibits cancer growth. It has also been shown to prevent heart disease by removing calcium from the arteries.
David Sinclair is a Harvard biologist who specializes in longevity science. He has built a career around the idea that certain supplements can slow biological aging. His research has led to books, podcasts, and biotech companies. He takes many different supplements, including vitamin D, vitamin K2, resveratrol, quercetin, NMN, spermidine, and TMG.
Resveratrol is a molecule found in the skin of grapes and other plants. It is a powerful sirtuin activator and has been shown to have life-extending properties in animals. It is also known for its anti-inflammatory, weight loss, and anti-cancer effects.
It interacts synergistically with NMN (Nicotinamide Mononucleotide), which is essential to activate the sirtuin genes and protects the DNA and epigenome. Sinclair takes 1 gram of resveratrol daily, usually mixed into his yogurt. He also takes 800 mg of metformin every night except on the days when he plans to exercise.
Quercetin is an antioxidant in the flavonoid family and a potent free radical scavenger. It has been shown to protect against heart disease, rheumatoid arthritis and some cancers. It also prevents the oxidation of unsaturated fatty acids and inhibits the enzymes that break down polyunsaturated fatty acids.
It has been shown in animal studies to reduce oxidative stress that can damage DNA and help cancer cells to self-destruct. It has been used in the treatment of several types of cancer including lung, breast, ovarian and colorectal cancers.
In addition, quercetin has antiviral properties and helps to fight against upper respiratory infections. It may even help prevent herpes outbreaks.
Sinclair is a prominent researcher in the field of aging and longevity. He has been taking several supplements that are able to increase NAD+ levels, which helps to delay aging. The NMN is a precursor of NAD+ and is available as a dietary supplement. NMN can help with cellular metabolism, reduce AGEs (advanced glycation end products), and increase energy levels.
It also helps in enhancing insulin sensitivity and reducing the risk of heart attacks. In addition to NMN, Sinclair also takes aspirin to reduce the risk of cardiovascular disease and cancer.
Spermidine is a polyamine that acts as an anti-aging supplement. It has been shown to promote cellular rejuvenation and increase longevity in mice. It also has antioxidant and anti-inflammatory properties. It is also thought to protect against cardiovascular disease by lowering arterial stiffness and inflammation. It may also help to reduce the growth of cancerous cells.
Spermidine has been shown to increase lifespan in many different animal models. It does this by activating autophagy, which is the process that recycles damaged cell components and maintains cellular homeostasis. It also increases lipid metabolism and inhibits inflammation. It has also been found to improve proteostasis, which is the balance of protein folding and degradation in the body.
Known as betaine, TMG helps add methyl groups to compounds and may help reduce homocysteine levels, which can increase the risk of heart disease. It is also believed to support the body’s detoxification systems and protect against oxidative stress.
A biological aging specialist, David Sinclair has made it his mission to live several decades longer than his chronological age. He does so by following a strict regimen that includes a special diet, exercise, health tracking and supplements.
He also takes a variety of vitamins and minerals, such as resveratrol, quercetin, and NMN. In addition, he tries to avoid foods containing microwaved plastic, excessive sun exposure, and X-rays.Read More